Why many who take antidepressants don't get relief


American research presented by long-time depression researcher Eva Redei at the neuro-science conference in Chicago, 2009, toppled two strongly held beliefs about depression. One is that stressful life events are a major cause of depression. Another is that neuro-transmitter imbalances in the brain trigger depressive episodes.

Both beliefs are significant because they form the basis on which anti-depressant medication currently in use has been developed.

But Redei and her team found that there was little overlap between depression-related genes and stress-related genes.